Ronald L. Koder Publications (as of 2/30/2009)

 

(25) Koder R.L. and Nanda, V.  Designing enzymes, from intuition to computation (2009) Nature Chemistry In Press

 

(24) Koder R.L., Anderson, R., Soloman, L.A., Reddy, K.S., Moser, C.M., Dutton, P.L. Design and Engineering of an O2 transport protein (2009) Nature 458:305-309

 

(23) Negron, C., Fufezan, C., Koder R.L. Geometric Constraints for Porphyrin Binding in Helical Protein Binding Sites (2009) Prot. Struct. Func. Bioinform. 74:400-416

 

(22) Lichtenstein, B.R., Cerda, J.F., Koder, R.L., Dutton, P.L. Reversible Proton Coupled Electron Transfer in a Peptide-incorporated Naphthoquinone Amino Acid (2009) Chem. Comm. 2: 168-170

 

(21) Anderson, R., Moser, C.M., Koder, R.L., Dutton, P.L. Controlling complexity and water penetration in functional  de novo protein design (2008) Biochem. Soc. Trans. 36:1106-1111

 

(20) Cerda, J.F., Koder, R.L., Lichtenstein, B.R., Moser, C.M., Miller, A.-F., Dutton, P.L. Hydrogen Bond-Free Flavin Redox Properties: Managing Flavins in Extreme Aprotic Solvents (2008) Org. & Biomol. Chem. 6:2204-2212

 

(19) Koder, R.L., Lichtenstein, B.R., Cerda, J.F., Miller, A.-F., Dutton, P.L. A Benzene Soluble Flavin Analogue (2007) Tetrahedron Letters 48: 5517-5520

 

(18) Koder, R. L., Walsh, J. D., Pometun, M. S.,Dutton, P. L., Wittebort, R. J.,Miller, A.-F. 15N Solid-State NMR Provides a Sensitive Probe of Oxidized Flavin Reactive Sites (2006) J. Amer. Chem. Soc. 128: 15200-15208

 

(17) Koder, R.L., Valentine, K. G., Cerda, J., Noy, D., Smith, K. M., Wand, A. J., Dutton, P. L. Nativelike Structure in Designed Four-Helix Bundles Driven by Buried Polar Interactions (2006) J. Amer. Chem. Soc. 128: 14450-14451

 

(16) Koder, R.L., Dutton, P.L. Looking Forward: The de novo Design of Proteins with Specific Function (2006) Dalt. Trans. 25: 3045-3051

 

(15) Miller, A.-F. Koder, R.L., Walsh, J.D., Zhang, P., Haynes, C.A., and Rogers, D.W.  Nitroreductase: Active Site Structure, Electronics and Thermodynamics (2005) Flavins and Flavoproteins 2005, pp 265-270

 

(14) Huang, S.L.*, Koder, R.L.*, Lewis, M.A., Wand A.J. and Dutton, P.L.  The HP-1 Maquette:  From an Apoprotein Structure to a Conformationally Specific Hemoprotein Designed to Promote Redox-Coupled Proton Exchange (2004) Proc. Nat. Acad. Sci. USA  101, 5536-41

 

(13) Discher, B., Koder, R.L., Moser, C.C., Dutton, P.L.  Hydrophilic to Amphiphilic Design in Redox Protein Maquettes (2003) Curr. Opin. Chem. Biol. 7, 741-748

 

(12) Koder, R.L., Haynes, C.H. Rodgers, M.A. and Miller, A.-F. Flavin Thermodynamics Explain the Oxygen Insensitivity of Enteric Nitroreductases. (2002) Biochemistry 41, 14197-14205

 

(11) Koder, R.L., Haynes, C.H. Rodgers, M.A. and Miller, A.-F.  A Spectroscopic Analysis of Inhibitor Binding to Enterobacter cloacae Nitroreductase.  (2002)  Flavins and Flavoproteins 2002, pp 265-270

 

(10) Miller, A.-F., Koder, R.L., Walsh, J.D., Haynes, C.A., Rodgers, M., Erdmann, H., Hecht, H.-J., Rodgers, D.W.  A Proposed Electrostatic Contribution to the Obligate Two-Electron, Oxygen-Insensitive Reactivity of Enteric Nitroreductase.  (2002) Flavins and Flavoproteins 2002, pp 293-298

 

(9) Nivinskas, H., Staskeviciene, S. Sarlauskas, J., Koder, R.L., Miller, A.-F., Cenas, N.  Two-Electron Reduction of Quinones by Enterobacter cloacae nitroreductase:  Quantitative Structure-Activity Relationships (2002) Arch. Biochem. Biophys. 403, 249-258

 

(8) Haynes, C.A., Koder. R.L., Miller, A.-F., Rodgers, D.W., Structures of Nitroreductase in Three States:  Effects of Inhibitor Binding and Reduction. (2002) J. Biol. Chem.  277, 11513-11520

 

(7) Koder, R.L., Oyedele, O., Miller, A.-F., Retro-nitroreductase, a Putative Ancestor of Enterobacter cloacae Nitroreductase. (2001) Antiox. Redox Cycling 3, 747-756

 

(6) Nivinskas, H., Koder, R.L., Anusevicius ,Z., Sarlauskas, J., Miller, A.-F. Cenas, N., Quantitative structure-activity relationships in two-electron reduction of nitroaromatic compounds by Enterobacter cloacae NAD(P)H:Nitroreductase (2000) Arch. Biochem. Biophys.  385, 170-178

 

(5) Schwartz, A.L., Yikilmaz, E., Vance, C.K., Vathyam, S., Koder, R.L., Miller, A.-F.,  Mutational and spectroscopic studies of the significance of the active site Gln to metal ion specificity in superoxide dismutases. (2000) J. Inorg. Biochem. 80, 247-256

 

(4) Koder, R.L, Rodgers, M.E. and Miller, A.-F., Flavin binding thermodynamics in Enterobacter cloacae nitroreductase. (1999)  Flavins and Flavoproteins 1999, pp 45-48

 

(3) Koder, R.L. and Miller, A.-F., Steady-state kinetic mechanism, stereospecificity, substrate and inhibitor specificity of Enterobacter cloacae nitroreductase. (1998) Biochim. Biophys. Acta 1387, 395-405.

 

(2) Koder, R.L. and Miller, A.F., Overexpression, isotopic labelling, and spectral characterization of Enterobacter cloacae nitroreductase. (1998) Prot. Exp. Pur. 13, 53-60.

 

(1) Beecher, B.S., Koder,  R.L., Tipton.  P.A.  Tartrate dehydrogenase-oxalate complexes – formation of a stable analog of a reaction intermediate complex. (1994) Arch. Biochem. Biophys. 315, 255-261